What Iambic Therapeutics does
Iambic Therapeutics is a clinical-stage, AI-native small-molecule drug discovery company (formerly Entos) that pairs physics-informed multimodal AI with automated high-throughput experimentation to design molecules and generate biological readouts on an iterative, “close-the-loop” cadence. The company’s stated approach is built around AI model development (e.g., Enchant for multimodal prediction and NeuralPLexer for protein–ligand structural insight) plus an operational pipeline that turns newly generated molecular designs into chemistry and biology data each week, with model retraining and iteration to support target profile optimization and candidate selection.