Samira NedungadiHead of Engineering
Research institute · Research orgs · Cambridge, MA
SecureBio is a U.S.-based nonprofit biosecurity organization developing technologies and research to reduce catastrophic biological risk, including risks involving pandemic pathogens and dual-use biotechnology. The organization’s work is organized around (1) Detection—pathogen-agnostic early-warning approaches intended to identify novel threats before they become widely detectable—and (2) AI and Biotechnology Risks—evaluating how frontier AI systems could contribute to biological misuse risk and exploring mitigations tied to measured risk thresholds.
SecureBio also describes itself as collaborating with academia, industry, and government, and as engaging with AI safety policy ecosystems (including NIST-related initiatives and European AI governance channels) to translate technical evaluation work into decision-relevant outputs.
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SecureBio discusses how evaluation strategy for dual-use virology may need to shift as frontier models approach or exceed calibrated human expert performance, and outlines approaches for continuing to gather relevant evidence indirectly.
Tracking pathogen variants with untargeted wastewater metagenomicsSecureBio publishes an update focused on tracking pathogen variants using untargeted wastewater metagenomics.
GPT-6 Astra Pre-Release Testing ReportSecureBio reports on pre-release testing of GPT-6 Astra for biological misuse-relevant capabilities.
Introducing VCT-v2 — the updated Virology Capabilities TestSecureBio describes an updated virology troubleshooting benchmark intended to be more shortcut-resistant, alongside reported observations about model accuracy changes since the original VCT release.
Building a three-day early-warning system for novel pathogensSecureBio describes a Detection-focused push funded by the OpenAI Foundation, including a plan to reduce end-to-end time and expand collection and validation.
SecureBio Detection Updates, August 2026SecureBio shares updates on the Detection program, including progress items described in its August 2026 update post.